Complete List of Side Effects

The NHS lists the following complete list of known side-effects of Solpadeine:

  • hypersensitivity reactions including allergic reactions, asthma, bronchospasm, low blood pressure, anaphylaxis or shock. Stop taking this medicine and seek immediate medical help if your face, tongue or throat swell, you have breathing difficulties or your heart rate is fast
  • gastro-intestinal bleeding, ulceration or perforation - these could be fatal. Stop taking this medicine and seek immediate medical advice if you have unusual stomach pain, discomfort, or have signs of gastro-intestinal bleeding
  • skin problems such as Stevens-Johnson Syndrome, erythema multiforme or toxic epidermal necrolysis. Stop taking this medicine and seek immediate medical advice if you get skin reactions such as urticaria, itching or skin rashes
  • aseptic meningitis - this has been reported in people who have autoimmune disorders such as systemic lupus erythematosus or mixed connective tissue disease. Seek immediate medical advice if you get symptoms such as a stiff neck, headache, nausea, vomiting, fever or are disorientated
  • blood and bone marrow problems - seek medical advice if you get symptoms such as fever, sore throat, mouth ulcers, flu-like symptoms, feel very tired or have unexplained bleeding and bruising
  • long-term use of codeine containing medicines may lead to addiction and withdrawal symptoms such as restlessness or irritability when the medicine is stopped
  • headache - long-term use of a painkiller for headaches can make them worse
  • worsening of asthma and bronchospasm
  • stomach pain
  • acute pancreatitis - this may happen in people who have had their gallbladder removed
  • nausea
  • drowsiness
  • indigestion
  • diarrhoea
  • flatulence
  • constipation
  • vomiting
  • worsening of ulcerative colitis or Crohn’s disease
  • dizziness
  • kidney problems or worsening of existing kidney problems
  • liver problems
  • hearing problems
  • high blood pressure
  • heart problems such as heart failure
  • thromboembolic events such as a stroke or heart attack
  • oedema
  • impaired female fertility
Unless otherwise stated, the content of this page is licensed under Creative Commons Attribution-ShareAlike 3.0 License